I've known about this for years, but it's helpful to see it verified in a meta-analysis.
"Depression is not a chemical imbalance in the brain and scientists have no idea how antidepressants work, a review by University College London has concluded."
"The researchers say that patients should not be told depression is
caused by a chemical imbalance, or informed that the SSRIs can correct
the problem. Although it is clear the antidepressants can work, they
must be doing so through a different route, the paper concludes."
You can read the article here: https://www.telegraph.co.uk/news/2022/07/20/depression-not-caused-chemical-imbalance/
Can you imagine big pharma coming out and saying in a TV ad, "Yeah, take this for depression. We have no idea what it's actually doing, but please let us take advantage of your misery to make money."
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